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KMID : 0861420100140020100
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Korean Journal of Nuclear Medicine Technology
2010 Volume.14 No. 2 p.100 ~ p.103
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The Analysis of Blood Glucose Level Difference According to the Exact Use of Blood Glucose Measurement Test Strips in18F-FDG Wholebody PET
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Park Soon-Ki
Lee Nam-Ki
NamGoong Chang-Kyoung
Jung Woo-Young
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Abstract
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Purpose: 18F-FDG wholebody PET is to evaluate the tumor using glucose metabolism. The blood glucose level is important factor that affects on a result of examination. High glucose levels may interfere with tumor targeting due to competitive inhibition of FDG uptake by D-glucose. The blood glucose level measurement test strips used in the blood glucose measurement are classified into the capillary blood measurement test strips and general purpose measurement test strips that can measure the venous blood and capillary blood altogether depends on cases. The purpose of the study was to compare the blood glucose measurements between simultaneously obtained capillary and venous blood samples using the capillary blood measurement test strips, general purpose measurement test strips.
Materials and Methods: A total of 46 subjects (32 males, 14 females) with a mean age of 57.3±12.3 years were enrolled. The blood glucose estimation was performed with a Optium Xceed Glucometer (Abbott). Simultaneous capillary and venous blood samples were obtained from each subject. Theblood glucose levels were measured using the capillary blood measurement test strips and general purpose measurement test strips. The capillary and venous measurements were compared using a pared t-test.
Results: The mean capillary and venous glucose values using the general purpose measurement test strips were
95.2±12.4 mg/dL and 104.1±14.4 mg/dL, giving a statistically significant difference (p<0.001) between the mean values for the capillary and venous glucose samples (9.0 mg/dL; 95% confidence interval (CI) -11.2 to -6.7). The mean capillary and venous glucose values using the capillary blood measurement test strips were 91.5±13.6 mg/dL and 108.6±16.2 mg/dL, giving a statistically significant difference (p<0.001) between the mean values for the capillary and venous glucose samples (16.6 mg/dL; 95% CI -20.2 to -13.0).
Conclusion: When measuring the blood glucose level before 18F-FDG PET examination, since the incorrect blood glucose
level can be measured, it should note to measure the blood glucose level of the venous blood by the capillary blood measurement test strips. Therefore the measurement variation can be reduced to fulfill the standardized measurement procedure with the suitable measurement test strips, the preparation of the PET examination will be able to be clearly confirmed. In addition, the standardized procedure of the following measurement on the area which is same at all times the blood area in the blood glucose measurement among a capillary or a vein will be needed.
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KEYWORD
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PET/CT , FDG , Blood glucose level
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